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Heart 1999;81:316-317 ( March )

Case report

Recurring myocardial infarction in a 35 year old woman I Bux-Gewehr, A Nacke, G E Feurle

I. Medizinische Klinik, DRK---Krankenhaus Neuwied, Marktstrabeta e 74, 56564 Neuwied, Germany

Correspondence to: Dr Feurle. email: bux-gewehr{at}t-online.de


Accepted for publication 3 September 1998

A 35 year old woman presented with acute myocardial infarction without any of the usual risk factors: she had never smoked; she had normal blood pressure; she did not have diabetes; plasma concentrations of total cholesterol and high and low density lipoprotein cholesterol, fibrinogen, homocysteine, and Lp(a) lipoprotein were normal. She was not taking oral contraceptives or any other medication. Coronary angiography showed occlusion of the left anterior descending coronary artery but no evidence of arteriosclerosis. Medical history disclosed a previous leg vein thrombosis with pulmonary embolism. Coagulation analysis revealed protein C deficiency. The recognition of protein C deficiency as a risk factor for myocardial infarction is important as anticoagulation prevents further thrombotic events, whereas inhibitors of platelet aggregation are ineffective.

Keywords: myocardial infarction; risk factors; protein C deficiency; anticoagulation

© 1999 by Heart


This article has been cited by other articles:


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I Y Tiong, M L Alkotob, and S Ghaffari
Protein C deficiency manifesting as an acute myocardial infarction and ischaemic stroke
Heart, February 1, 2003; 89(2): e7 - 7.
[Abstract] [Full Text] [PDF]


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