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a Department of Oral
Medicine, Eastman Dental Institute for Oral Healthcare Sciences,
University College London, 256 Gray's Inn Road, London WC1X 8LD,
UK, b Department of Paediatric
Dentistry, Eastman Dental Institute, c Maxillofacial and Dental Department,
Great Ormond Street Hospital for Children, London WC1N 3JH, UK
Correspondence to: Dr Lucas v.lucas{at}eastman.ucl.ac.uk
Accepted 11 September
2000
OBJECTIVE
To estimate the cumulative
exposure to bacteraemia from dental procedures currently recommended
for antibiotic prophylaxis and compare this with cumulative exposure
from dental procedures not recommended for prophylaxis.
DESIGN
Retrospective analysis.
SETTING
University and teaching
hospital maxillofacial and dental department.
PATIENTS
136 children with severe
congenital cardiac disease attending for dental treatment between 1993 and 1998 and for whom full records were available. Each dental
procedure was tallied.
MAIN OUTCOME MEASURES
Cumulative
exposure per annum to "non-prophylaxis procedures"; cumulative
exposure per annum to "prophylaxis procedures".
RESULTS
Cumulative exposure to
bacteraemia from prophylaxis procedures was not significantly greater
than from non-prophylaxis procedures.
CONCLUSIONS
The data raise important
questions about the appropriateness of current guidelines for
antibiotic prophylaxis of bacterial endocarditis.
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